At Circova, we believe healthy circulation shouldn't be an afterthought. Cold hands, heavy legs, and afternoon energy crashes are often early signs your body is trying to tell you something — so we built a formula around ingredients studied for supporting the vessel lining itself, not just masking symptoms.
Our Approach
Every batch of Circova is formulated with full label transparency — no hidden proprietary blends, no filler doses. Just cayenne pepper, grape seed oil, hawthorn, beetroot, turmeric, and a handful of other researched botanicals, at doses we're not afraid to show you.
Scientific References
"Dietary capsaicin activates TRPV1 channels and increases eNOS phosphorylation, supporting nitric oxide-mediated vasodilation." — Blood Circulation Stimulation Properties of Cayenne Pepper: A Review, ResearchGate.
"Beetroot inorganic nitrate supplementation significantly decreased arterial stiffness and increased endothelial function (flow-mediated dilation)." — ScienceDirect, 2021.
"Hawthorn extract's blood pressure-lowering effect has been linked to nitric oxide-mediated vasodilation, evaluated via flow-mediated dilation of the brachial artery." — PubMed/PMC, 2012.
"High-dose grape seed proanthocyanidin extract (400mg/day) significantly decreased systolic blood pressure by 13 mmHg after 12 weeks." — Odai T, et al., Nutrients, 2019. DOI: 10.3390/nu11122844
"Curcumin supplementation has been shown in a meta-analysis of randomized controlled trials to significantly improve flow-mediated dilation." — Hallajzadeh et al., Phytotherapy Research, 2019.
"Piperine (from black pepper) acts as a vasodilator on vascular smooth muscle and enhances the absorption of co-administered compounds like curcumin." — European Journal of Pharmacology.
"A meta-analysis of randomized controlled trials found cinnamon supplementation significantly reduced both systolic and diastolic blood pressure in adults." — Clinical Nutrition ESPEN, 2020.
"A controlled human study found one month of berberine supplementation improved flow-mediated dilation and reduced oxidative stress." — Atherosclerosis, ScienceDirect.
"A 2025 meta-analysis of 13 randomized controlled trials found ginseng supplementation significantly increased flow-mediated dilation and nitric oxide levels." — BMC Complementary Medicine and Therapies, 2025.
These studies examine the individual ingredients in Circova, not the Circova formula itself. Individual results may vary. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.